TCTAP A-075 Identification of High-risk Patent Foramen Ovale Associated with Cryptogenic Stroke

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Patent Foramen Ovale and Cryptogenic Stroke

To the Editor: The articles by Meier et al.1 and Carroll et al.2 and the corresponding editorial by Messé and Kent3 (March 21 issue) illustrate a major problem in clinical trials. When it is not obvious which of two therapies is better, sufficient numbers of events are essential to reach a conclusion. Performing a prospective, randomized trial is not enough. In the PC Trial (Clinical Trial Comp...

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Patent Foramen Ovale and Cryptogenic Stroke

Stroke aetiology may be classified according to the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria.2 As per TOAST classification cryptogenic stroke is defined as stroke not attributable to definite cardioembolic source, large artery atherosclerosis or small artery disease. Cryptogenic stroke includes patients with less wellestablished potential causes of cardiac embolism, such as...

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Patent foramen ovale and cryptogenic stroke.

The presence of a patent foramen ovale (PFO) has been found to be associated with an increased risk of cryptogenic stroke in many case-control studies. This paper reviews the current understanding of the pathophysiology and diagnosis of PFO, and therapeutic options of patients with PFO and cryptogenic stroke.

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Is closure recommended for patent foramen ovale and cryptogenic stroke? Patent foramen ovale in cryptogenic stroke: not to close.

A quick PubMed search reveals an abundance of editorials, reviews, and opinion pieces on the subject of patent foramen ovale (PFO) management, and this is now the fourth published article on this topic that has adapted William Shakespeare’s classic words from Hamlet to describe the conundrum that faces neurologists, cardiologists, and their patients.1–3 The degree to which this title has been o...

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Outcome of patients with cryptogenic stroke and patent foramen ovale.

OBJECTIVES The aim was to estimate the recurrence rate and to define subgroups at increased risk for recurrent cerebral ischaemia in patients with patent foramen ovale (PFO) and so called cryptogenic stroke due to paradoxical embolism. METHODS Patent foramen ovale was diagnosed in 318 patients with otherwise unexplained ischaemic stroke or transient ischaemic attack (TIA). One hundred and fif...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2019

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2019.03.111